ATE2316T1 - Dipeptid (pyro)glu-his(dnp)-oh und verfahren zur herstellung von lh-rh und lh-rh-analoga unter verwendung dieses dipeptids. - Google Patents
Dipeptid (pyro)glu-his(dnp)-oh und verfahren zur herstellung von lh-rh und lh-rh-analoga unter verwendung dieses dipeptids.Info
- Publication number
- ATE2316T1 ATE2316T1 AT80100635T AT80100635T ATE2316T1 AT E2316 T1 ATE2316 T1 AT E2316T1 AT 80100635 T AT80100635 T AT 80100635T AT 80100635 T AT80100635 T AT 80100635T AT E2316 T1 ATE2316 T1 AT E2316T1
- Authority
- AT
- Austria
- Prior art keywords
- dipeptide
- pyro
- dnp
- glu
- analogues
- Prior art date
Links
- 108010016626 Dipeptides Proteins 0.000 title 2
- XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 title 2
- 101000904177 Clupea pallasii Gonadoliberin-1 Proteins 0.000 title 1
- HKTRDWYCAUTRRL-YUMQZZPRSA-N Glu-His Chemical compound OC(=O)CC[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CN=CN1 HKTRDWYCAUTRRL-YUMQZZPRSA-N 0.000 title 1
- 239000000579 Gonadotropin-Releasing Hormone Substances 0.000 title 1
- 101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 title 1
- WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2905502A DE2905502C2 (de) | 1979-02-14 | 1979-02-14 | Verfahren zur Herstellung von LH-RH bzw. LH-RH-Analoga und Pyroglutamyl-N↑i↑m↑-dinitrophenyl-histidin |
| EP80100635A EP0014911B1 (de) | 1979-02-14 | 1980-02-07 | Dipeptid (pyro)Glu-His(Dnp)-OH und Verfahren zur Herstellung von LH-RH und LH-RH-Analoga unter Verwendung dieses Dipeptids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE2316T1 true ATE2316T1 (de) | 1983-02-15 |
Family
ID=6062835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT80100635T ATE2316T1 (de) | 1979-02-14 | 1980-02-07 | Dipeptid (pyro)glu-his(dnp)-oh und verfahren zur herstellung von lh-rh und lh-rh-analoga unter verwendung dieses dipeptids. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4275001A (en]) |
| EP (1) | EP0014911B1 (en]) |
| JP (2) | JPS55111449A (en]) |
| AR (1) | AR227386A1 (en]) |
| AT (1) | ATE2316T1 (en]) |
| AU (1) | AU532335B2 (en]) |
| CA (1) | CA1144160A (en]) |
| DE (2) | DE2905502C2 (en]) |
| DK (1) | DK148085C (en]) |
| ES (1) | ES488382A1 (en]) |
| HU (1) | HU182067B (en]) |
| IL (1) | IL59362A (en]) |
| ZA (1) | ZA80817B (en]) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3020941A1 (de) * | 1980-06-03 | 1981-12-17 | Hoechst Ag, 6000 Frankfurt | Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung |
| DE3421303A1 (de) * | 1984-06-08 | 1985-12-12 | Hoechst Ag, 6230 Frankfurt | Salze aus 3-hydroxy-4-oxo-3,4-dihydro-1,2,3-benzotriazin und amino-verbindungen |
| GB2187461A (en) * | 1986-02-03 | 1987-09-09 | Medical Res Council | Monitoring method for the synthesis of a linear of amino acid residues |
| AT388918B (de) * | 1987-10-08 | 1989-09-25 | Hoechst Ag | Aminosaeure-oobt-ester |
| US20040265285A1 (en) * | 1999-04-15 | 2004-12-30 | Monash University | Normalization of defective T cell responsiveness through manipulation of thymic regeneration |
| US20040258672A1 (en) * | 1999-04-15 | 2004-12-23 | Monash University | Graft acceptance through manipulation of thymic regeneration |
| US20040241842A1 (en) * | 1999-04-15 | 2004-12-02 | Monash University | Stimulation of thymus for vaccination development |
| US20070274946A1 (en) * | 1999-04-15 | 2007-11-29 | Norwood Immunoloty, Ltd. | Tolerance to Graft Prior to Thymic Reactivation |
| US20040259803A1 (en) * | 1999-04-15 | 2004-12-23 | Monash University | Disease prevention by reactivation of the thymus |
| AUPR074500A0 (en) * | 2000-10-13 | 2000-11-09 | Monash University | Treatment of t cell disorders |
| US20050020524A1 (en) * | 1999-04-15 | 2005-01-27 | Monash University | Hematopoietic stem cell gene therapy |
| US20060088512A1 (en) * | 2001-10-15 | 2006-04-27 | Monash University | Treatment of T cell disorders |
| US20080279812A1 (en) * | 2003-12-05 | 2008-11-13 | Norwood Immunology, Ltd. | Disease Prevention and Vaccination Prior to Thymic Reactivation |
| RU2442791C1 (ru) * | 2010-07-08 | 2012-02-20 | Закрытое Акционерное Общество "Фарм-Синтез" | Способ получения бусерелина и промежуточные соединения для его получения |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2211101A1 (de) * | 1972-03-08 | 1973-09-13 | Hoechst Ag | Neues dekapeptid mit hormon-wirkung |
| NO139560C (no) * | 1972-04-29 | 1979-04-04 | Takeda Chemical Industries Ltd | Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater |
| US3888836A (en) * | 1972-05-30 | 1975-06-10 | Merck & Co Inc | Pentapeptide intermediate of lhrh and derivatives thereof |
| US3931138A (en) * | 1973-03-13 | 1976-01-06 | Abbott Laboratories | N-carbobenzoxy-pyroglutamyl-histidine |
| IT1045531B (it) * | 1973-10-19 | 1980-05-10 | Serono Ist Farm | Prodesso per la preparazione di l.piroslutamil.l.istidil.l.prolinamide sintetica,trh |
| US4083967A (en) * | 1973-11-01 | 1978-04-11 | Burroughs Wellcome Co. | Nona- and decapeptides |
| US3959248A (en) * | 1974-04-03 | 1976-05-25 | Merck & Co., Inc. | Analogs of thyrotropin-releasing hormone |
| NL7505590A (nl) * | 1974-05-18 | 1975-11-20 | Hoechst Ag | Werkwijze voor het bereiden van peptiden met lh-rh/fsh-rh-werking. |
| ZA754724B (en) * | 1974-08-28 | 1976-06-30 | Hoffmann La Roche | Amide |
| NZ181036A (en) * | 1975-06-12 | 1978-12-18 | A Schally | Luteinising hormone releasing hormone analogues and intermediates therefor |
| GB1559610A (en) * | 1975-10-31 | 1980-01-23 | Armour Pharma | Synthesis of peptides |
| US4218439A (en) * | 1977-07-14 | 1980-08-19 | The Salk Institute For Biological Studies | Peptide which inhibits gonadal function |
| HU177134B (en) * | 1977-07-18 | 1981-07-28 | Richter Gedeon Vegyeszet | Process for preparing angiotensin ii analogues containing alpha-hydroxy-acid in position 1 with angiotensin ii antagonist activity |
-
1979
- 1979-02-14 DE DE2905502A patent/DE2905502C2/de not_active Expired
-
1980
- 1980-02-07 AT AT80100635T patent/ATE2316T1/de not_active IP Right Cessation
- 1980-02-07 DE DE8080100635T patent/DE3061712D1/de not_active Expired
- 1980-02-07 EP EP80100635A patent/EP0014911B1/de not_active Expired
- 1980-02-08 ES ES488382A patent/ES488382A1/es not_active Expired
- 1980-02-11 IL IL59362A patent/IL59362A/xx not_active IP Right Cessation
- 1980-02-12 US US06/120,924 patent/US4275001A/en not_active Expired - Lifetime
- 1980-02-12 AR AR279939A patent/AR227386A1/es active
- 1980-02-13 HU HU80319A patent/HU182067B/hu unknown
- 1980-02-13 CA CA000345595A patent/CA1144160A/en not_active Expired
- 1980-02-13 DK DK61180A patent/DK148085C/da active
- 1980-02-13 AU AU55481/80A patent/AU532335B2/en not_active Expired
- 1980-02-13 ZA ZA00800817A patent/ZA80817B/xx unknown
- 1980-02-14 JP JP1611780A patent/JPS55111449A/ja active Granted
-
1987
- 1987-02-12 JP JP62028396A patent/JPS62277397A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK148085C (da) | 1985-08-12 |
| JPS6345398B2 (en]) | 1988-09-09 |
| IL59362A (en) | 1982-12-31 |
| EP0014911A2 (de) | 1980-09-03 |
| DK61180A (da) | 1980-08-15 |
| EP0014911A3 (en) | 1980-11-26 |
| AU5548180A (en) | 1980-08-21 |
| ZA80817B (en) | 1981-01-28 |
| DE2905502A1 (de) | 1980-09-04 |
| HU182067B (en) | 1983-12-28 |
| AR227386A1 (es) | 1982-10-29 |
| EP0014911B1 (de) | 1983-01-26 |
| JPS55111449A (en) | 1980-08-28 |
| JPS6317839B2 (en]) | 1988-04-15 |
| DE2905502C2 (de) | 1982-07-15 |
| JPS62277397A (ja) | 1987-12-02 |
| US4275001A (en) | 1981-06-23 |
| CA1144160A (en) | 1983-04-05 |
| DE3061712D1 (en) | 1983-03-03 |
| ES488382A1 (es) | 1980-10-01 |
| IL59362A0 (en) | 1980-05-30 |
| DK148085B (da) | 1985-02-25 |
| AU532335B2 (en) | 1983-09-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |